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Description

This commentary explores how artificial intelligence (AI) is profoundly affecting the biological enterprise, serving both as a powerful tool for scientific advancement and as a potential vector for misuse. The authors explain that AI can accelerate research, improve diagnostics, and enhance biodefense, but it also lowers barriers to creating or modifying biological agents and can be exploited for harmful ends. The dual effects make AI a "double-edged sword" that challenges existing governance, detection systems, and deterrence frameworks in biosecurity. Responsible integration of AI into biology requires policies that balance innovating with safeguards, strengthened international cooperation, and adaptive oversights to ensure that AI's benefits are realized while minimizing risks to public health and national security.

Document Type

Article

Topic(s)

Biological and Chemical Issues, Emerging Science and Technologies, National Security

Region(s)

United States

Publication Date

12-8-2025

Keywords

artificial intelligence, AI in biology, biosecurity risks, dual-use technology, biodefense, detection and attribution, biological governance, synthetic biology, national security technology, AI ethics, strategic risk, research acceleration, biological enterprise

Artificial Intelligence: A Double-Edged Sword in Support and Subversion of the Biological Weapons Convention; Part One: Framing the Issues

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